A randomized controlled trial on the efficacy of Neelidaladi kera in Dushivisha with signs and symptoms of Kitibha Kushta.

A randomized controlled trial on the efficacy of Neelidaladi kera in Dushivisha with signs and symptoms of Kitibha Kushta.

Dr.Bijaya Kumar Gupta

2006-2009

Under the guidance of

Dr. S.R. Manju, MD(Ay), D.A.T. &Dr. C. Vijayalakshmi, MD(Ay), D.A.T.

Abstract

At present context people are more exposed to various kinds of poisons in food as well as in environment which in turn leads to accumulation of Dushivisha inside the human body. As a result Dushivishaja twak vikaras are becoming more common. Kitibha Kushta is one of them. It has got similarity with certain varieties of psoriasis which affect nearly 3% of world population by influencing person`s personal and family life.

In the present scenario the traditional knowledge of health care is gaining momentum. It has been noticed, the skin diseases like Kitibha kushta is effectively managed by some of the traditional Visha Vaidya of Kerala by use of Neelidadi kera.So far no efforts has been made scientifically to evaluate the efficacy of this drug. Here is an attempt to find the efficacy of Neelidadi kera in Dushivisha with signs and symptoms Kitibha kushta.So that the traditional claim can be proved and established.

The study was designed as randomized controlled clinical trial. Patients were selected from O.P.D. of Department of Agadatantra and Government Ayurveda College, Thiruvananthapuram as per as the inclusion criteria. The 30 patients were distributed into study and control group by simple random sampling method. Out of that sixteen patients (study group) were received Patoladigana kashaya internally along with external application of Neelidadi kera and rest fourteen patients (control group) were given only Patoladigana kashaya internally without any external application for one month and were followed up for 15 days. Strict diet (pathya ahara and vihara) was advised during the study period. Both subjective and objective parameters along with PASI score and necessary routine Lab investigations were considered for clinical assessment. The data so obtained were statistically analyzed, tables, charts were drawn for interpretation and understanding the result.

Both the groups individually showed significant result on interpretation of data related to response of treatment. But among both, study group showed more significant results on assessment of clinical features like Kandu, Rooksha, Kinakhara sparsa, Parusha and also risk of any toxic effect was not observed during the study period. Neelidaladi kera is also found to be cost effective. Hence we come to a conclusion that the Neelidaladi kera is effective in subsiding Dushivisha with signs and symptoms of Kitibha kushta and worth using in practice.

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